Phytochemical composition, antioxidant and wound healing activities of Teucrium polium subsp. capitatum (L.) Briq. essential oil
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Date
2020-11
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Abstract
Teucrium poliumis widely used in Algerian folk medicine as to treat wounds. The aim of this study
was to evaluate the chemical composition, antioxidant and wound healing properties of Teucrium
polium essential oil. The composition was obtained by a combination of GC-FID and GC-MS
analyses. The antioxidant activity was evaluated by in vitro assays (total antioxidant capacity,
DPPH and bleaching of β-carotene). The in vivo wound healing potential of an ointment containing
10% of T. polium essential oil was investigated. The main components were in this order: β-pinene,
germacrene, α-pinene, myrcene, limonene, bicyclogermacrene, trans-β-guaiene, spathulenol and
β-bourbonene. Teucrium polium essential oil displayed a moderate antioxidant activity. The in
vivo experiments showed that 10% OEO accelerated the wound healing process in comparison
with controls. This study provides a scientific rationale for the use of Teucrium polium essential oil in
the treatments of wounds.
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Keywords
Teucrium polium; essential oil; chemical composition; antioxidant; wound healing