Anti-inflammatory and hemostatic effects of Linaria reflexa Desf
| dc.contributor.author | Thamere, Cheriet | |
| dc.date.accessioned | 2020-02-11T09:42:47Z | |
| dc.date.available | 2020-02-11T09:42:47Z | |
| dc.date.issued | 2019-09 | |
| dc.description.abstract | The work presented here was aimed to investigate the in vivo anti-inflammatory and in vitro hemostatic activities of Linaria reflexa extract and to establish the relationship between its bioactivity and chemical composition. Twenty-three secondary metabolites were identified, most of them are good anti-inflammatory agents, in line with data by carrageenin-induced rat paw edema assays of the n-butanol extract showing high anti-inflammatory inhibition (63.90%) of edema swelling in the rat paw at the dose 200mg/kg after 4 h. Furthermore, both extent of inflammatory response and tissue injury were prevented keeping the levels of rate myeloperoxidase (60.16%) and of malondialdehyde, which is the final product of lipid peroxidation generated by free radicals (58.58%). The same extract showed also a remarkable hemostatic effect established by measuring the coagulation time of decalcified plasma (45 s), related to its flavonoid glycosides content | en_US |
| dc.identifier.uri | http://dspace.univ-msila.dz:8080//xmlui/handle/123456789/19225 | |
| dc.language.iso | en | en_US |
| dc.publisher | Université de M'sila | en_US |
| dc.subject | flavones; acids; antiinflammatory; hemostatic; Linaria reflexa | en_US |
| dc.title | Anti-inflammatory and hemostatic effects of Linaria reflexa Desf | en_US |
| dc.type | Article | en_US |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- AntiinflammatoryandhemostaticeffectsofLinariareflexaDesf.pdf
- Size:
- 990.38 KB
- Format:
- Adobe Portable Document Format
- Description:
License bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- license.txt
- Size:
- 1.71 KB
- Format:
- Item-specific license agreed upon to submission
- Description: